Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR.
ANGPTL4 contains one fibrinogen C-terminal domain.
ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer.
The homooligomer unprocessed form is able to interact with the extracellular matrix.
ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis.
ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage.
ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 27.9 kDa.
The protein migrates as 31-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human Angiopoietin-like 4 (166-406), His Tag (AN4-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 166 - Ser 406 (Accession # Q9BY76-1).
