Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily.
TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling.
TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 46.3 kDa.
The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Cynomolgus DR3, Fc Tag (TN5-C5257) is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Gly 203 (Accession # G7NTB5-1).
Species Reactivity：Cynomolgus
Host：HEK293
Tag：C-Fc
Exp Region：Gln 20 - Gly 203
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：G7NTB5-1
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
