Descriptopn：Interferon gamma （IFNγ） is a dimerized soluble cytokine that is predominately produced by natural killer and natural killer T cells during the innate immune response and by T cells once antigen specific immunity develops.
IFNγ is crucial for immunity against intracellular pathogens and for tumor control.
Release of IFNγ is controlled mostly by the cytokines IL-12 and IL-18.
Serum IFNγ levels have been shown to be elevated in active cases of systemic lupus erythematosus （SLE） and may be associated with the development of autoimmune diseases like SLE.
