The ELN/CCP7 FISH Probe Kit is designed to detect the human ELN gene located on chromosome band 7q11.23, along with the number of chromosome 7 copies per cell.
Abnormal expression due to gains or losses of this gene – also known as WS, WBS, SVAS, ADCL1– has been observed in prostate carcinomas well as other malignancies.
The ELN gene is frequently deleted in Williams Syndrome (WS) individuals.