The PCM1-JAK2 Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human PCM1 and JAK2 genes located on chromosome bands 8p22 and 9p24.1, respectively.
Rearrangements involving portions of these two genes, the PCM1 gene – also known as JTK10 or RET/PCM-1 – and the JAK2 gene – also called JTK10 – have been observed in some chronic （CML） and acute myeloid leukemias （AML）, acute lymphoid leukemias （ALL）, myelodysplastic syndrome （MDS）, and other myeloid and lymphoid malignancies.
