The IGK-IRF4/DUSP22 Dual Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human IGK locus and the region around the IRF4 and DUSP22 genes, located on chromosome bands 2p11.2 and 6p25.3, respectively.
Rearrangements between the two regions (the IGK locus – also known as IGK@ –) have been observed in B-cell lymphomas, leukemias and other malignancies.