The IGH-IRF4/DUSP22 Dual Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human IGH locus and the region around the IRF4 and DUSP22 genes, located on chromosome bands 14q32.33 and 6p25.3, respectively.
Rearrangements between the two regions (the IGK locus – also known as IGK@ –) have been observed in many leukemia and lymphoma types.