The SNRPN/CCP15 FISH Probe Kit is designed to detect the human SNRPN gene located on chromosome band 15q11.2, along with the number of chromosome 15 copies per cell.
Altered expression of this gene – also known as SMN, PWCR, SM-D, sm-N, RT-LI, HCERN3, SNRNP-N, SNURF-SNRPN – has been observed in some solid tumor types.
Paternal copy deletion of this gene is observed in Prader-Willi Syndrom （PWS） individuals.
