The CCP13,18,21,X,Y FISH Probe Kit is designed to simultaneously determine the copy number of human chromosomes 13, 18, 21, X and Y, and to detect copy number aberrations in these chromosomes, in metaphase and interphase blood and tissue cells.
Trisomies of chromosomes 13, 18 and 21 as well as sex chromosome aneuploidies are the by far most common prenatal chromosomal aberrations.
While the panel can also reveal other copy number defects including mono-, tetra- and polyploidies and other anomalies, a diverse range of specific abnormalities may not be detected by this panel such as localized inversions or balanced intrachromosomal translocations, centromeric polymorphisms, some microdeletions or microduplications, and other defect types.
