The RB1/CCP15 FISH Probe Kit is designed to detect the human RB1 gene located on chromosome band 13q14.2, along with the number of chromosome 15 copies per cell.
Abnormal expression of the RB1 gene – also known as RB, pRb, OSRC, pp110, p105-Rb, PPP1R130 or p110-RB1– and aneuploidy of the chromosome 15 have been observed in retinoblastoma, sarcomas and various other tumor types.
