The NF1/CCP17 FISH Probe is designed to detect the human NF1 gene located on chromosome band 17q11.2, along with the number of chromosome 17 copies per cell.
Abnormal expression of this gene – also known as WSS, NFNS or VRN – has been observed in some juveline leukemias, gastrointestinal stromal tumors and other tumor types.
Mutations and deletions at the NF1 locus are observed in Watson Syndrome and in Neurofibromatosis type I microdeletion syndrome individuals.
