The TP53/ATM/D13S319/LAMP1/CCP12FISH Probe Kit is designed to simultaneously detect rearrangements involving the human TP53, ATM, D13S319 and LAMP1 genes, located on chromosome bands 17q13.1, 11q22.3, 13q14.2, and 13q34, respectively.
Gains and losses of these loci have been observed in B-cell chronic lymphocytic leukemia (CLL) and other neoplasms.