The NF2/CCP22 FISH Probe Kit is designed to detect the human NF2 gene located on chromosome band 22q12.2, along with the number of chromosome 22 copies per cell.
Abnormalities in NF2 – also known as ACN, SCH, BANF or merlin-1 – occur in ataxia telangiectasia, and have also been observed in cancers such as meningeal cancer, pleural cancer, soft tissue cancer and other malignancies.