TheRB1/CKS1B FISH Probe Kitis designed to detect the humanRB1gene, located on chromosomes band 13q14.2, and the CKS1B gene on chromosome band 1q21.3.
Abnormal expression of the RB1 gene has been observed in retinoblastoma, soft tissue and bone sarcomas and various other cancers.
Amplification and overexpression of CKS1B has been found in multiple cancer types including myeloma, breast and ovarian cancer, lymphoma, renal carcinoma and others.
