The D20S108/CCP8 FISH Probe Kit is designed to detect the human D20S108 STS marker regions located on chromosome band 20q12, along with the number of chromosome 8 copies per cell.
Abnormalities in the D20S108 region are frequently found in myelodysplastic syndrome (MDS), acute myeloid leukemia (AML) and other myeloid disorders.
Trisomy 8 is frequently reported in myeloid and lymphoid neoplasias.