The FOLR1 Break Apart FISH Probe Kit is designed to detect rearrangements in the human FOLR1 gene located on chromosome band 11q13.4.
In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other FOLR1 aberrations such as deletions or amplifications.
Rearrangements and abnormal expression of the FOLR1 gene – also known as FBP, FOLR, NCFTD or FRalpha – are associated with various types of cancers such as breast, ovarian, fallopian tube, non-small cell lung and other malignancies.
