TheCAMTA1 Break Apart FISH Probe Kitis designed to detect rearrangements in the humanCAMTA1gene located on chromosome band1p36.31.
In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify otherCAMTA1aberrations such as deletions or amplifications.
Rearrangements and abnormal expression of theCAMTA1gene – also known asKIAA0833orCANPMR– have been observed inneuroblastoma, glioma, colon cancer and other malignancies.
