The CHEK1/CCP11 FISH Probe Kit is designed to detect the human CHEK1 gene located on chromosome band 11q24.2, along with the number of chromosome 11 copies per cell.
Abnormalities in CHEK1 – also known as CHK1 – occur in lung adenocarcinoma, colon adenocarcinoma, endometrial endometrioid adenocarcinoma, melanoma and other malignancies.