The AXIN1/CCP16 FISH Probe Kit is designed to detect the human AXIN1 gene located on chromosome band 16p13.3, along with the number of chromosome 16 copies per cell.
Mutations in AXIN1 – also known as AXIN or PPP1R49 – have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, medullablastomas and other malignancies.