The CHFR/CCP12 FISH Probe Kit is designed to detect the human CHFR gene located on chromosome band 12q24.33, along with the number of chromosome 12 copies per cell.
Abnormalities in CHFR – also known as RNF116 or RNF196 – occur in various types of cancers such as colorectal, breast, lung, acute myeloid leukemia (AML), B-cell non-Hodgkin lymphoma and other malignancies.