The KDM5A/CCP12 FISH Probe Kit is designed to detect the human KDM5A gene located on chromosome band 12p13.33, along with the number of chromosome 12 copies per cell.
Abnormalities in KDM5A – also known as RBP2, RBBP2 or RBBP-2 – have been observed in colon adenocarcinoma, lung adenocarcinoma, breast invasive ductal carcinoma, endometrial endometrioid adenocarcinoma, melanoma and other malignancies.