The SKI/CCP1 FISH Probe Kit is designed to detect the human SKI gene located on chromosome band 1p36.33-p36.32, along with the number of chromosome 1 copies per cell.
Deregulation of this gene – also known as SGS or SKV – has been observed in some lymphomas and in bone, kidney, gastric and other solid tumor types.
Mutations in the gene have been found in the very rare Shprintzen–Goldberg syndrome.
