The DLEU1/TP53 FISH Probe Kit is designed to detect the human DLEU1 and TP53 genes located on chromosome bands 13q14.2 and 17p13.1, respectively.
Rearrangements and abnormal expression of the DLEU1 gene region – also known as BCMS, DLB1, LEU1, LEU2, XTP6, BCMS1, DLEU2, LINC00021 or NCRNA00021 – and the TP53 gene – also known as P53, BCC7, LFS1 or TRP53 – have been observed in B-cell chronic lymphocytic leukemia （CLL） and other malignancies.
