The ETV6-NTRK3 Dual Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human ETV6 and NTK3 genes, located on chromosome bands 12p13.2 and 15q25.3, respectively.
ETV6 is also known as TEL, THC5 or TEL/ABL.
NTRK3 is also known as TRKC, GP145-TrkC or gp145(trkC).
Rearrangements involving portions of these two genes have been observed in acute myeloid leukemia (AML) and other malignancies.