The PDCD1LG2/CCP9 FISH Probe Kit is designed to detect the human PDCD1LG2 gene located on chromosome band 9p24.1, along with the number of chromosome 9 copies per cell.
Abnormal expression of the PDCD1LG2 gene – also known as PDL2, PDCD1L2, bA574F11.2, PD-L2, CD273, Btdc or B7DC – has been observed in several lymphoma subtypes, in melanoma, and in various types of solid tumors like esophageal adenocarcinoma and others.