The TCF3-PBX1 Single Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human TCF3 and PBX1 genes located on chromosome bands 19p13.3 and 1q23.3, respectively.
Rearrangements between the two genes, the TCF3 gene – also known as E2A, E47, ITF1, VDIR, TCF-3 or bHLHb21, have been observed in B-cell acute lymphoblastic leukemias （B-ALL） and other tumor types.
