TheIGL-MYC Dual Fusion/Translocation LR (long-range) FISH Probe Kitis designed to detect rearrangements involving the humanIGLandMYCgenes, located on chromosome bands 22q11.22 and 8q24.21, respectively.
IGL is also known as IGL@ or IGLC6.
MYC is also known as MRTL, MYCC, c-Myc or bHLHe39.
Rearrangements involving portions of these two genes have been observed in several B-cell lymphoma subtypes, especially Burkitt lymphoma, and other malignancies.