The CCP18/CCPX/CCPY FISH Probe Kit is designed to simultaneously determine the copy number of human chromosomes 18, X and Y, and to detect copy number aberrations in these chromosomes, in metaphase and interphase blood and tissue cells.
Trisomies of chromosome 18 as well as sex chromosome aneuploidies are common prenatal chromosomal aberrations.
While the panel can also reveal other copy number defects including mono-, tetra- and polyploidies and other anomalies, a diverse range of specific abnormalities may not be detected by this panel such as localized inversions or balanced intrachromosomal translocations, centromeric polymorphisms, some microdeletions or microduplications, and other defect types.
