The EPOR Break Apart FISH Probe Kit is designed to detect rearrangements in the human EPOR gene located on chromosome band 19p13.2.
In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other EPOR aberrations such as deletions or amplifications.
Rearrangements and abnormal expression of the EPOR gene – also known as EPO-R – have been observed in B-cell acute lymphoblastic leukemia （B-ALL）.
