The COL1A1-PDGFB Single Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human COL1A1 and PDGFB genes located on chromosome bands 17q21.33 and 22q13.1, respectively.
Rearrangements between the two genes, the COL1A1 gene – also known as OI4 – and the PDGFB gene – also called IBGC5, PDGF-2, PDGF2, SIS, SSV or c-sis, have been observed in dermatofibrosarcoma protuberans （DFSP） and some other tumor types.
