The PAFAH1B1/CCP17 FISH Probe Kit is designed to detect the human PAFAH1B1 gene located on chromosome band 17p13.3, along with the number of chromosome 17 copies per cell.
Abnormal expression of this gene – also known as MDS, LIS1, LIS2, MDCR, NudF, PAFAH – has been observed in small-cell lung carcinoma and several other solid tumor types.
Loss of the gene is observed in Miller-Dieker Syndrome patients.
