The FIP1L1/CHIC2 FISH Probe Kit is designed to detect rearrangements in a region involving the human FIP1L1 and CHIC2 genes located on chromosome band 4q12.
Rearrangements around the FIP1L1 gene region with an interstitial deletion at the CHIC2 gene region have been observed in diverse eosinophilia-associated hematologic disorders like hyperseosinophilic syndrome （HES）, systemic mastocytosis （SM） and chronic eosinophilic leukemia （CEL）.
