The TERT/EGR1 FISH Probe Kit is designed to detect the human TERT gene on chromosome band 5p15.33, and the EGR1 gene on chromosome band 5q31.2.
Abnormalities in TERT – also known as TP2, TRT, CMM9, EST2, TCS1, hTRT, DKCA2, DKCB4, hEST2 or PFBMFT1 – and abnormalities in EGR1 – also known as ERBB, HER1, mENA, ERBB1, PIG61 or NISBD2 – have been observed in myeloid malignancies, fibrosarcoma, lung, brain, breast, skin, prostate liver and various other cancer types.