The CUX1/VIPR2 FISH Probe Kit is designed to detect the human CUX1 gene located on chromosome band 7q22.1 and the VIPR2 gene on chromosome band 7q36.3.
Expression of the CUX1 gene – also known as CDP, CUX, p75, CASP, CDP1, COY1, Clox, p100, p110, p200, CUTL1, GOLIM6, CDP/Cut, Cux/CDP or Nbla10317 – has been observed elevated in pancreatic, breast and other cancers.
Duplications and other anomalies in the region of the VIPR2 gene – also called VPAC2, VPAC2R, VIP-R-2, VPCAP2R, PACAP-R3, DUP7q36.3, PACAP-R-3, C16DUPq36.3 – are associated with schizophrenia, prenatal malformations and some intestinal malignancies.