The SMAD6/CCP15 FISH Probe Kit is designed to detect the human SMAD6 gene located on chromosome bands 15q22.31, along with the number of chromosome 15 copies per cell.
Abnormalities in SMAD6 – also known as MADH7, MADH6, HsT17432, or AOVD2 – are associated with cardiac valve defects, developmental deficiencies, lung neoplasms and other malignancies.