The RPN1/CCP3 FISH Probe Kit is designed to detect the human RPN1 gene located on chromosome band 3q21.3, along with the number of chromosome 3 copies per cell.
Abnormalities in RPN1 – also known as RBPH1 or OST1 – have been observed in acute myeloid leukemias (AML), prostate tumors and other malignancies.