The PNOC/CCP8 FISH Probe Kit is designed to detect the human PNOC gene located on chromosome band 8p21.1, along with the number of chromosome 8 copies per cell.
Rearrangements and abnormal expression of the PNOC gene – also called OFQ, N/OFQ, PPNOC or ppN/OFQ – have been associated with various heritable anatomical and developmental abnormalities.