The MCL1/CCP1 FISH Probe Kit is designed to detect the human MCL1 gene located on chromosome band 1q21.3, along with the number of chromosome 1 copies per cell.
Abnormal expression or rearrangements of the MCL1 gene – also known as mcl1/EAT, bcl2-L-3, TM, Mcl-1, MCL1S, MCL1L, MCL1-ES, EAT or BCL2L3 – have been observed in chronic myelogenous leukemia (CML), multiple myeloma (MM), B-cell non-Hodgkin's lymphomas and other malignancies.