The KMT2A/CCP11 FISH Probe Kit is designed to detect the human KMT2A gene located on chromosome band 11q23.3, along with the number of chromosome 11 copies per cell.
Abnormal expression of the KMT2A gene – also known as HRX, MLL, MLL1, TRX1, ALL-1, CXXC7, HTRX1, MLL1A, WDSTS, MLL/GAS7 or TET1-MLL – have been observed in a large number of acute leukemias and other malignancies.