The FGFR4/D5S23, D5S721 FISH Probe Kit is designed to detect the human FGFR4 gene located on chromosome band 5q35.2 and the D5S23-D5S721 marker region on chromosome band 5p15.2.
Abnormalities in FGFR4 – also known as CD334, JTK2 or TKF – have been observed in various cancer types such as prostate cancer, melanoma, hepatocellular carcinoma, lung cancer, breast cancer, gastric cancer, colorectal cancer, pancreatic cancer and others.