The CD37/ZNF443 FISH Probe Kit is designed to detect rearrangements involving the human CD37 gene located on chromosome band 19q13.33, along with the region around ZNF443 gene located on chromosome band 19p13.2 measuring the integrity of chromosome 19.
Abnormal expression of the CD37 gene – also called GP52-40 or TSPAN26 – is upregulated in Burkitt's lymphoma and other B-cell malignancies, and expressed in a number of solid tumor types as well.
