The BRAF/CCP7 FISH Probe Kit is designed to detect the human BRAF gene located on chromosome band 7q34, along with the number of chromosome 7 copies per cell.
Abnormalities in BRAF – also known as v-raf murine sarcoma viral oncogene homolog B1, BRAF1 or RAFB1 – have been found in solid tumors like melanoma, colorectal cancer, ovarian cancer, papillary thyroid cancer and other malignancies.