The MN1-ETV6 Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human MN1 and ETV6 genes located on chromosome bands 22q12.1 and 12p13.2, respectively.
Rearrangements between the two gene regions, the MN1 gene – also known as dJ353E16.2, MGCR1-PEN, MGCR1 or MGCR – and the ETV6 gene – also called EL, THC5 or TEL/ABL, have been observed in myelodysplastic syndrome （MDS）, acute myeloid leukemia （AML） and other malignancies.
