TheMNX1-ETV6 Dual Fusion/Translocation FISH Probe Kitis designed to detect rearrangements involving the humanMNX1andETV6genes, located on chromosome bands 7q36.3 and 15q25.3, respectively.
MNX1 is also known as HB9, HLXB9, SCRA1 or HOXHB9.
ETV6 is also known as TEL, THC5 or TEL/ABL.
Rearrangements involving portions of these two genes have been observed in acute myeloid leukemia (AML) and many other predominantly myeloproliferative neoplasms.