The TP53/ATM FISH Probe Kit is designed to detect rearrangements involving the human TP53 and ATM genes, located on chromosome bands 17p13.1 and 11q22.3, respectively.
Abnormalities in both genes, the TP53 gene – also known as P53, BCC7, LFS1 or TRP53 – and the ATM gene – also called AT1, ATA, ATC, ATD, ATE, ATDC, TEL1 or TELO1, have been reported in a number of leukemia types and other malignancies.
