The PTEN/CCP10 FISH Probe Kit is designed to detect the human PTEN gene located on chromosome band 10q23.31, along with the number of chromosome 10 copies per cell.
Loss or abnormal expression of the PTEN gene – also known as BZS, DEC, CWS1, GLM2, MHAM, TEP1, MMAC1, PTEN1 or 10q23del – is common in gliomas and prostate cancer and has been observed in a variety of other heritable and sporadic tumor types and conditions.