The PDGFRA/CCP4 FISH Probe Kit is designed to detect the human PDGFRA gene located on chromosome band 4q12, along with the number of chromosome 4 copies per cell.
Rearrangements and abnormal expression of the PDGFRA gene – also known as CD140A, PDGFR2, PDGFR-2 or RHEPDGFRA – have been observed in gastrointestinal stromal tumors （GIST）, lung adenocarcinoma and other hematologic and solid tissue disorders.
