The FN1-FGFR1 Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human FN1 and FGFR1 genes located on chromosome bands 2q35 and 8p11.23, respectively.
Rearrangements between the two gene regions, the FN1 gene – also known as CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS or MSF – and the FGFR1 gene – also called BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, or bFGF-R-1, have been observed in a number of hematological and solid tumor types, and other conditions.
