The PRKAR1A-RET Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human PRKAR1A and RET genes located on chromosome bands 17q24.2 and 10q11.21, respectively.
Rearrangements between the two genes, the PRKAR1A gene – also called ACRDYS1, ADOHR, CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1 or TSE1 – and the RET gene – also known as PTC, MTC1, HSCR1, MEN2A, MEN2B, RET51, CDHF12, CDHR16 or RET-ELE1, have been observed in a subtype of papillary thyroid carcinoma （PTC2）.
