The KIF5B-RET Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human KIF5B and RET genes located on chromosome bands 10p11.22 and 10q11.21, respectively.
Rearrangements and abnormal expression of the KIF5B gene – also known as KNS, KINH, KNS1, UKHC or HEL-S-61 – and between the two genes have been observed in lung adenocarcinoma and other tumor types.